Biocompatibility research programmes
The in vitro evaluation of biocompatibility
Preliminary evaluations of the biocompatibility of a new treatment or biomaterial can be performed on cell cultures, helping to cut development costs and the excessive use of animal testing.
Development of a 3D oral mucosal model
Model tissues are intended to provide safe, reproducible test beds for new clinical procedures, and help us gain a more complete understanding of existing treatments. Unlike animal tests, model tissues are usually based on human cells, acquired during patient biopsies. These cells are cultured in a controlled environment to provide material for tests as required.
The effectiveness of these models systems relies on how well they reproduce the tissue of interest. This poses considerable experimental challenges.